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Pushing the Frontiers of Cancer Research: Highlights from the Frontiers in Cancer Science Conference 2023.

作者信息

Lee Yi Fei, Chen Leilei, Chew Valerie, Chow Edward Kai-Hua, Deng Lih-Wen, Hunziker Walter, Lee Ann Siew Gek, Leong Geraldine, Ngeow Joanne, Pervaiz Shazib, Sabapathy Kanaga, Skanderup Anders J, Sundar Raghav, Tay Yvonne, Virshup David M, Wong Sunny H, Tergaonkar Vinay, Tam Wai Leong

机构信息

Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore.

Cancer Science Institute of Singapore, National University of Singapore, Singapore.

出版信息

Cancer Res. 2024 Apr 15;84(8):1195-1198. doi: 10.1158/0008-5472.CAN-24-0721.

Abstract

The 15th annual Frontiers in Cancer Science (FCS) conference gathered scientific experts who shared the latest research converging upon several themes of cancer biology. These themes included the dysregulation of metabolism, cell death, and other signaling processes in cancer cells; using patient "omics" datasets and single-cell and spatial approaches to investigate heterogeneity, understand therapy resistance, and identify targets; innovative strategies for inhibiting tumors, including rational drug combinations and improved drug delivery mechanisms; and advances in models that can facilitate screening for cancer vulnerabilities and drug testing. We hope the insights from this meeting will stimulate further progress in the field.

摘要

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