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Revolutionizing Neurological Disorder Treatment: Integrating Innovations in Pharmaceutical Interventions and Advanced Therapeutic Technologies.

作者信息

Arora Rimpi, Baldi Ashish

机构信息

Pharma Innovation Lab., Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda 151001, India.

出版信息

Curr Pharm Des. 2024;30(19):1459-1471. doi: 10.2174/0113816128284824240328071911.


DOI:10.2174/0113816128284824240328071911
PMID:38616755
Abstract

Neurological disorders impose a significant burden on individuals, leading to disabilities and a reduced quality of life. However, recent years have witnessed remarkable advancements in pharmaceutical interventions aimed at treating these disorders. This review article aims to provide an overview of the latest innovations and breakthroughs in neurological disorder treatment, with a specific focus on key therapeutic areas such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, and stroke. This review explores emerging trends in drug development, including the identification of novel therapeutic targets, the development of innovative drug delivery systems, and the application of personalized medicine approaches. Furthermore, it highlights the integration of advanced therapeutic technologies such as gene therapy, optogenetics, and neurostimulation techniques. These technologies hold promise for precise modulation of neural circuits, restoration of neuronal function, and even disease modification. While these advancements offer hopeful prospects for more effective and tailored treatments, challenges such as the need for improved diagnostic tools, identification of new targets for intervention, and optimization of drug delivery methods will remain. By addressing these challenges and continuing to invest in research and collaboration, we can revolutionize the treatment of neurological disorders and significantly enhance the lives of those affected by these conditions.

摘要

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本文引用的文献

[1]
Mild cognitive impairment in Huntington's disease: challenges and outlooks.

J Neural Transm (Vienna). 2024-4

[2]
Mitochondria and Brain Disease: A Comprehensive Review of Pathological Mechanisms and Therapeutic Opportunities.

Biomedicines. 2023-9-7

[3]
Exploring the Frontiers of Neuroimaging: A Review of Recent Advances in Understanding Brain Functioning and Disorders.

Life (Basel). 2023-6-29

[4]
Effects of transcranial direct current stimulation and transcranial magnetic stimulation in patients with fibromyalgia. A systematic review.

Neurologia (Engl Ed). 2023

[5]
New insight into gut microbiota and their metabolites in ischemic stroke: A promising therapeutic target.

Biomed Pharmacother. 2023-6

[6]
Combined Therapeutics: Future Opportunities for Co-therapy with Thrombectomy.

Neurotherapeutics. 2023-4

[7]
Cell therapies for spinal cord injury: a review of the clinical trials and cell-type therapeutic potential.

Brain. 2023-7-3

[8]
The Ketogenic Diet in Children with Epilepsy: A Focus on Parental Stress and Family Compliance.

Nutrients. 2023-2-20

[9]
Clinical Impact of the Gene on Diazepam for the Management of Alcohol Withdrawal Syndrome.

J Pers Med. 2023-2-3

[10]
An Overview of the History, Pathophysiology, and Pharmacological Interventions of Multiple Sclerosis.

Cureus. 2023-1-2

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