Hossain Md Jubayer, Azad Abul Kalam, Shahid Md Shahadat Bin, Shahjahan Muhibullah, Ferdous Jannatul
Population Health Studies Division, Center for Health Innovation, Research Action, and Learning - Bangladesh (CHIRAL Bangladesh) Dhaka Bangladesh.
Department of Microbiology Jagannath University Dhaka Bangladesh.
Health Sci Rep. 2024 Apr 11;7(4):e2039. doi: 10.1002/hsr2.2039. eCollection 2024 Apr.
Antibiotic resistance presents a significant global public health challenge, particularly for urinary tract infections (UTIs), and is notably severe in developing countries. Surveillance of the antimicrobial susceptibility patterns of UTI-causing bacteria is crucial for effective treatment selection. This study aimed to analyze these patterns in bacteria isolated from the urine samples of patients at Mughda Medical College Hospital, Dhaka, Bangladesh.
A retrospective study (January 2019 to December 2020) at Mugdha Medical College and Hospital, Dhaka, examined clinical and laboratory data from patients with positive urine cultures (≥10 CFU/mL). The study classified patients into four age groups: children (1-<18 years), young adults (18-<33 years), middle-aged adults (33-50 years), and old adults (>50 years). The standard Kirby-Bauer method was used to assess antibiotic sensitivity to 28 common antibiotics.
Among 243 positive urine cultures in both community- and hospital-acquired UTIs, was the most common uropathogen (65.84%), followed by spp. (12.34%), spp. (8.23%), and other types of bacteria.
Old adults are particularly vulnerable to UTIs, with being the predominant causative agent in the study region. The observed antimicrobial resistance patterns underscore the necessity of judicious antibiotic selection to effectively treat UTIs across different age groups.
抗生素耐药性是一项重大的全球公共卫生挑战，尤其是对于尿路感染（UTIs）而言，在发展中国家尤为严重。监测引起尿路感染的细菌的抗菌药敏模式对于有效选择治疗方法至关重要。本研究旨在分析从孟加拉国达卡穆格达医学院医院患者尿液样本中分离出的细菌的这些模式。
在达卡穆格达医学院医院进行了一项回顾性研究（2019年1月至2020年12月），检查了尿培养阳性（≥10 CFU/mL）患者的临床和实验室数据。该研究将患者分为四个年龄组：儿童（1 - <18岁）、青年成年人（18 - <33岁）、中年成年人（33 - 50岁）和老年人（>50岁）。采用标准的 Kirby - Bauer 方法评估对28种常见抗生素的药敏情况。
在社区获得性和医院获得性尿路感染的243份阳性尿培养样本中， 是最常见的尿路病原体（65.84%），其次是 属（12.34%）、 属（8.23%）和其他类型细菌。
老年人特别容易患尿路感染， 在研究区域是主要病原体。观察到的抗菌耐药模式强调了明智选择抗生素以有效治疗不同年龄组尿路感染的必要性。
原文中部分细菌名称未完整给出，所以译文里也保留了这种不完整状态。
