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与自身免疫性甲状腺炎相关的类固醇反应性脑病,以帕金森综合征为表现

Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis Presenting With Parkinsonism.

作者信息

Hicham Guemouz, Naji Yahya, Hrouch Wafa, Laadami Sara, Adali Nawal

机构信息

Neurology Department, Agadir University Hospital, Agadir, MAR.

Neurology, Neurosciences Innovation Cognition Ethique (NICE) Research Team, Rein Endocrinologie Gastroentérologie Neurosciences Ethique (REGNE) Research Laboratory, Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, MAR.

出版信息

Cureus. 2024 Mar 14;16(3):e56184. doi: 10.7759/cureus.56184. eCollection 2024 Mar.

Abstract

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare condition defined as encephalopathy with a positive antithyroid antibody. We report the case of a 52-year-old woman who presented with Parkinsonism associated with Hashimoto's thyroiditis. A few similar cases have been reported. Our patient responded well to corticosteroids with a significant reduction in symptoms. Diagnosis can pose a significant challenge in SREAT cases because of its variable clinical presentation. Therefore, we recommend evaluating thyroid function and thyroid autoantibodies in the context of acute and subacute encephalopathy. In the elderly population, SREAT, as a cause of Parkinsonism, should not be forgotten because of its simple treatment and significant improvements in neurological symptoms.

摘要

自身免疫性甲状腺炎相关的类固醇反应性脑病(SREAT)是一种罕见疾病,定义为伴有抗甲状腺抗体阳性的脑病。我们报告一例52岁女性患者,其表现为与桥本甲状腺炎相关的帕金森综合征。已有少数类似病例报道。我们的患者对皮质类固醇反应良好,症状显著减轻。由于SREAT病例临床表现多样,诊断可能面临重大挑战。因此,我们建议在急性和亚急性脑病的情况下评估甲状腺功能和甲状腺自身抗体。在老年人群中,SREAT作为帕金森综合征的一个病因,因其治疗简单且神经症状有显著改善,不应被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a1/11015944/18dc32b7d73f/cureus-0016-00000056184-i01.jpg

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