Kayali Leen, Thiab Ghadah, Inam Hashim, Nolte Justin
Internal Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Neurology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Cureus. 2024 Jul 25;16(7):e65369. doi: 10.7759/cureus.65369. eCollection 2024 Jul.
Steroid-responsive encephalopathy associated with thyroiditis (SREAT) is a rare autoimmune disorder characterized by cognitive dysfunction. SREAT is frequently overlooked despite its profound impact on patients and the healthcare system. This case report details a male patient who experienced a series of neuropsychiatric symptoms over several months, ultimately attributed to SREAT, emphasizing the critical impact of delayed recognition. The case underscores the diverse and often complicated presentations of SREAT, advocating for the timely consideration of autoimmune encephalopathy in patients with unexplained neuropsychiatric symptoms and abnormal thyroid function. Furthermore, it illustrates the effectiveness of steroids in managing SREAT and the challenges posed by long-term steroid use. Comprehensive diagnostic criteria and tailored treatment strategies are crucial for improving patient outcomes in this rare but impactful disorder.
与甲状腺炎相关的类固醇反应性脑病(SREAT)是一种以认知功能障碍为特征的罕见自身免疫性疾病。尽管SREAT对患者和医疗系统有深远影响,但它经常被忽视。本病例报告详细介绍了一名男性患者,他在几个月内出现了一系列神经精神症状,最终归因于SREAT,强调了延迟诊断的严重影响。该病例强调了SREAT表现多样且往往复杂,主张对有不明原因神经精神症状和甲状腺功能异常的患者及时考虑自身免疫性脑病。此外,它说明了类固醇在治疗SREAT方面的有效性以及长期使用类固醇带来的挑战。全面的诊断标准和量身定制的治疗策略对于改善这种罕见但有影响的疾病的患者预后至关重要。