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基于表面等离子体激元和超材料的病毒检测生物传感平台综述。

A review on plasmonic and metamaterial based biosensing platforms for virus detection.

作者信息

Hassan Mohammad Muntasir, Sium Farhan Sadik, Islam Fariba, Choudhury Sajid Muhaimin

机构信息

Department of Electrical and Electronic Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh.

Institute of Information and Communication Technology, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh.

出版信息

Sens Biosensing Res. 2021 Aug;33:100429. doi: 10.1016/j.sbsr.2021.100429. Epub 2021 May 20.

Abstract

Due to changes in our climate and constant loss of habitat for animals, new pathogens for humans are constantly erupting. SARS-CoV-2 virus, become so infectious and deadly that they put new challenge to the whole technological advancement of healthcare. Within this very decade, several other deadly virus outbreaks were witnessed by humans such as Zika virus, Ebola virus, MERS-coronavirus etc. and there might be even more infectious and deadlier diseases in the horizon. Though conventional techniques have succeeded in detecting these viruses to some extent, these techniques are time-consuming, costly, and require trained human-resources. Plasmonic metamaterial based biosensors might pave the way to low-cost rapid virus detection. So this review discusses in details, the latest development in plasmonics and metamaterial based biosensors for virus, viral particles and antigen detection and the future direction of research in this field.

摘要

由于我们的气候变化以及动物栖息地的不断丧失,新的人类病原体不断出现。严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒变得极具传染性和致命性,给医疗保健的整个技术进步带来了新挑战。在这十年内,人类还目睹了其他几起致命病毒爆发,如寨卡病毒、埃博拉病毒、中东呼吸综合征冠状病毒等,未来可能还会出现更具传染性和致命性的疾病。尽管传统技术在一定程度上成功检测到了这些病毒,但这些技术耗时、成本高,且需要训练有素的人力资源。基于表面等离激元超材料的生物传感器可能为低成本快速病毒检测铺平道路。因此,本综述详细讨论了基于表面等离激元和超材料的生物传感器在病毒、病毒颗粒和抗原检测方面的最新进展以及该领域的未来研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd3/8133828/b760e13300d2/gr1_lrg.jpg

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