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基于等离子体的用于病毒诊断的生物传感器的综合评述。

A comprehensive review on plasmonic-based biosensors used in viral diagnostics.

机构信息

Department of Electrooptics and Photonics Engineering, School of Electrical and Computer Engineering, The Ilse-Katz Nanoscale and Technology Center, Ben Gurion University of the Negev, Beer Sheva, 84105, Israel.

Jožef Stefan Institute, Jamova cesta 30, SI-1000, Ljubljana, Slovenia.

出版信息

Commun Biol. 2021 Jan 15;4(1):70. doi: 10.1038/s42003-020-01615-8.

Abstract

The proliferation and transmission of viruses has become a threat to worldwide biosecurity, as exemplified by the current COVID-19 pandemic. Early diagnosis of viral infection and disease control have always been critical. Virus detection can be achieved based on various plasmonic phenomena, including propagating surface plasmon resonance (SPR), localized SPR, surface-enhanced Raman scattering, surface-enhanced fluorescence and surface-enhanced infrared absorption spectroscopy. The present review covers all available information on plasmonic-based virus detection, and collected data on these sensors based on several parameters. These data will assist the audience in advancing research and development of a new generation of versatile virus biosensors.

摘要

病毒的增殖和传播已成为对全球生物安全的威胁,当前的 COVID-19 大流行就是一个例证。病毒感染的早期诊断和疾病控制一直至关重要。病毒检测可以基于各种等离子体现象来实现,包括传播表面等离子体共振(SPR)、局域 SPR、表面增强拉曼散射、表面增强荧光和表面增强红外吸收光谱。本综述涵盖了基于等离子体的病毒检测的所有现有信息,并根据几个参数收集了这些传感器的数据。这些数据将帮助读者推进新一代多功能病毒生物传感器的研究和开发。

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