Institute of Analytical Psychology, City University of Macau, 999078 Macau, China; Oriental Academy for Analytical Psychology, 510080 Guangzhou, Guangdong, China; Department of Mental Health, Heze City Mudan People's Hospital, 274000 Heze, Shandong, China.
Actas Esp Psiquiatr. 2024 Apr;52(2):107-113. doi: 10.62641/aep.v52i2.1585.
Aerobic exercise therapy can improve brain function and promote positive emotions in patients with depression. This study aims to improve the efficacy of aerobic exercise therapy in depression by investigating the influencing factors therein.
This study conducted a single-centre cross-sectional analysis of clinical data from 211 depression patients who received aerobic exercise therapy at Heze Mudan People's Hospital from May 2021 to May 2023. After excluding 10 patients who did not meet the inclusion criteria, the final cohort included 201 patients. The clinical data of patients with effective treatment and patients with ineffective treatment were collected, such as socio-demographic characteristics, disease status, depression degree, treatment compliance, and social support. Binary Logistic regression was used to analyze the factors affecting the clinical efficacy of aerobic exercise therapy in patients.
Among the 201 patients, the effective and ineffective rates of aerobic exercise therapy were 80.10% (161/201) and 19.90% (40/201), respectively. When analysed as groups, no significant differences were observed between the effective group (EG) and ineffective group (IG) regarding gender, body mass index, course of depression, age of first onset, mental symptoms, years of education, personal income, or marital status (p > 0.05). However, the EG exhibited a reduced probability of family history of mental illness, smoking history, and severity of depression (p < 0.05), along with higher treatment compliance and Social Support Rating Scale (SSRS) scores compared to the IG (p < 0.05). Binary logistic regression analysis revealed that smoking history, family history of mental illness, treatment compliance, depression, and SSRS score were the primary influencing factors on the efficacy of aerobic exercise therapy (p < 0.05).
Smoking history, family history of mental illness, treatment compliance, severity of depression, and social support are the primary influencing factors on the efficacy of aerobic exercise therapy in patients with depression. These factors should be emphasized during follow-up treatment to optimize the clinical treatment effect.
有氧运动疗法可以改善抑郁症患者的大脑功能并促进积极情绪。本研究旨在通过研究其中的影响因素来提高抑郁症患者有氧运动疗法的疗效。
本研究对 2021 年 5 月至 2023 年 5 月在菏泽市牡丹人民医院接受有氧运动疗法的 211 例抑郁症患者的临床资料进行了单中心横断面分析。排除 10 例不符合纳入标准的患者后，最终纳入 201 例患者。收集了有效治疗和无效治疗患者的临床资料，如社会人口学特征、疾病状况、抑郁程度、治疗依从性和社会支持。采用二项逻辑回归分析有氧运动疗法对患者临床疗效的影响因素。
在 201 例患者中，有氧运动疗法的有效率和无效率分别为 80.10%（161/201）和 19.90%（40/201）。分析组间差异时，有效组（EG）和无效组（IG）在性别、体重指数、抑郁病程、首发年龄、精神症状、受教育年限、个人收入或婚姻状况方面无显著差异（p>0.05）。然而，EG 具有较低的精神病史和吸烟史发生率，抑郁严重程度较低（p<0.05），同时治疗依从性和社会支持评定量表（SSRS）评分高于 IG（p<0.05）。二项逻辑回归分析显示，吸烟史、精神病史、治疗依从性、抑郁程度和 SSRS 评分是有氧运动疗法疗效的主要影响因素（p<0.05）。
吸烟史、精神病史、治疗依从性、抑郁程度和社会支持是影响抑郁症患者有氧运动疗法疗效的主要因素。在随访治疗中应重视这些因素，以优化临床治疗效果。
