Vargervik K, Harvold E P
Am J Orthod. 1985 Sep;88(3):242-51. doi: 10.1016/s0002-9416(85)90219-2.
A clinical study was designed to disclose the effects of activator treatment in the correction of Class II malocclusions. The rationale for the use of the activator appliance was based on the premise that correction of distocclusion can be achieved by inhibition of forward growth of the maxilla, inhibition of mesial migration of maxillary teeth, inhibition of maxillary alveolar height increase and extrusion of mandibular molars, increased growth of the mandible, anterior relocation of the glenoid fossa, mesial movement of mandibular teeth, and combinations of these effects. The appliance, as designed for this study, could potentially have an effect on all of these factors. Measurements were obtained from cephalometric head films obtained at 6-month intervals. Matched-pairs analyses of control versus treatment change after 6 months and after 1 year of treatment were done on 36 and 29 pairs, respectively. Pretreatment versus treatment changes were analyzed on 33 subjects by means of the spline regression analysis; posttreatment versus treatment changes were analyzed on 18 subjects by means of the Student Newman-Keuls multiple comparison test. The matched-pairs analyses of mean values demonstrated significant reduction in forward growth of the maxilla, uprighting of the maxillary incisors, reduced overjet, leveling of the mandibular occlusal plane, improved molar relationship, downward and forward relocation of the glenoid fossae, increased advancement of all mandibular structures, increased face profile angle, and increased lower face height. The two longitudinal analyses yielded similar findings, but some differences were noted. Because rather severe dental malocclusions were corrected, the slight average inhibition of maxillary growth and the anterior relocation of glenoid fossae alone could not account for the correction of the Class II dental arch relationship. It was therefore concluded that, in addition to the statistically significant changes, smaller changes occurred in several areas without being consistent enough or of a large enough magnitude to become statistically significant in the analyses of mean values. Comparison of group averages may mask treatment effects that significantly contribute to the correction of malocclusions in individual cases.
一项临床研究旨在揭示激活器治疗对矫治安氏II类错牙合畸形的效果。使用激活器矫治器的理论依据基于这样一个前提,即通过抑制上颌的向前生长、抑制上颌牙齿的近中移动、抑制上颌牙槽高度增加以及下颌磨牙的伸长、促进下颌生长、关节窝向前移位、下颌牙齿的近中移动以及这些作用的联合,可以实现远中错牙合的矫治。为本研究设计的矫治器可能会对所有这些因素产生影响。测量数据来自每隔6个月拍摄的头影测量片。分别对36对和29对受试者进行了6个月和1年治疗后对照组与治疗组变化的配对分析。对33名受试者通过样条回归分析进行治疗前与治疗后变化的分析;对18名受试者通过学生-纽曼-库尔斯多重比较检验进行治疗后与治疗后变化的分析。平均值的配对分析表明,上颌向前生长显著减少、上颌切牙直立、覆盖减小、下颌牙合平面变平、磨牙关系改善、关节窝向下向前移位、所有下颌结构向前移动增加、面部轮廓角增加以及下面部高度增加。两项纵向分析得出了相似的结果,但也注意到了一些差异。由于相当严重的牙列错牙合畸形得到了矫治,仅上颌生长的轻微平均抑制和关节窝的向前移位不足以解释安氏II类牙弓关系的矫治。因此得出结论,除了具有统计学意义的变化外,在几个区域还发生了较小的变化,但在平均值分析中不够一致或幅度不够大,以至于未达到统计学意义。组平均值的比较可能会掩盖对个别病例错牙合畸形矫治有显著贡献的治疗效果。