异维A酸与阿维A酯治疗泛发性脓疱型和慢性银屑病的对比
Isotretinoin vs etretinate therapy in generalized pustular and chronic psoriasis.
作者信息
Moy R L, Kingston T P, Lowe N J
出版信息
Arch Dermatol. 1985 Oct;121(10):1297-301.
PMID:3862363
Abstract
The clinical response to isotretinoin (13-cis-retinoic acid) in 11 patients with generalized pustular psoriasis was evaluated. Control of pustulation and systemic symptoms was achieved in ten cases, but additional therapy was required to produce complete clearing of all psoriatic lesions. Also, the efficacy of isotretinoin and etretinate in the treatment of chronic plaque psoriasis was compared in 29 patients. Isotretinoin was found to be less effective than etretinate in the treatment of chronic plaque psoriasis.
摘要
评估了11例泛发性脓疱型银屑病患者对异维A酸（13-顺式维甲酸）的临床反应。10例患者的脓疱和全身症状得到控制，但需要额外治疗才能使所有银屑病皮损完全消退。此外，比较了29例患者中异维A酸和阿维A酯治疗慢性斑块状银屑病的疗效。结果发现，在治疗慢性斑块状银屑病方面，异维A酸的效果不如阿维A酯。
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