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Retraction Note: Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway.

作者信息

Jo Min Gi, Ikram Muhammad, Jo Myeung Hoon, Yoo Lang, Chung Kwang Chul, Nah Seung-Yeol, Hwang Hongik, Rhim Hyewhon, Kim Myeong Ok

机构信息

Division of Life Science and Applied Life Science (BK21 Plus), College of Natural Sciences, Gyeongsang National University, Jinju, 52802, Republic of Korea.

Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.

出版信息

Mol Neurobiol. 2024 Jul;61(7):4926. doi: 10.1007/s12035-024-04175-8.

DOI:10.1007/s12035-024-04175-8
PMID:38625622
Abstract
摘要

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Retraction Note: Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway.撤稿说明:人参炔三醇通过Nrf2/HO-1通路减轻MPTP诱导的黑质纹状体多巴胺能神经元损失和α-突触核蛋白积累。
Mol Neurobiol. 2024 Jul;61(7):4926. doi: 10.1007/s12035-024-04175-8.
2
Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway.金雀异黄素通过 Nrf2/HO-1 通路减轻 MPTP 诱导的黑质纹状体多巴胺能神经元丢失和 α-突触核蛋白的积累。
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Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress.可溶性环氧化物水解酶抑制减轻 MPTP 诱导的黑质纹状体多巴胺能系统神经毒性:涉及α-突触核蛋白聚集和内质网应激。
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Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.帕金森毒素MPTP给药后黑质多巴胺能神经元中α-突触核蛋白上调。
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7,8-dihydroxyflavone Ameliorates Motor Deficits Via Suppressing α-synuclein Expression and Oxidative Stress in the MPTP-induced Mouse Model of Parkinson's Disease.7,8-二羟基黄酮通过抑制MPTP诱导的帕金森病小鼠模型中的α-突触核蛋白表达和氧化应激来改善运动功能障碍。
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Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons.条件性转基因小鼠表达 C 端截断的人类 alpha-突触核蛋白 (alphaSyn119),表现出纹状体多巴胺减少,而黑质纹状体多巴胺能神经元没有丢失。
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Rosmarinic acid protects against MPTP-induced toxicity and inhibits iron-induced α-synuclein aggregation.迷迭香酸可防止 MPTP 诱导的毒性,并抑制铁诱导的α-突触核蛋白聚集。
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引用本文的文献

1
Water extract of ginseng alleviates parkinsonism in MPTP-induced Parkinson's disease mice.人参水提取物可缓解 MPTP 诱导的帕金森病小鼠的帕金森病。
PLoS One. 2024 Sep 20;19(9):e0296424. doi: 10.1371/journal.pone.0296424. eCollection 2024.