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远志多糖的制备、结构特征及药理活性综述

Preparation, structural characteristics and pharmacological activity of polysaccharides from Polygala tenuifolia: A review.

作者信息

Li Yuanyuan, Zheng Huimin, Yao Qiuhui, Ma Yongbo, Wang Lei, Liu Qian, Liu Yuhong

机构信息

School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.

College of Pharmacy, Qinghai Nationalities University, Xining, 810007, China.

出版信息

Carbohydr Res. 2024 May;539:109117. doi: 10.1016/j.carres.2024.109117. Epub 2024 Apr 10.

DOI:10.1016/j.carres.2024.109117
PMID:38626569
Abstract

Polygala tenuifolia is a traditional Chinese medicine with a long history of application, with the efficacy of suppressing cough, calming asthma, tranquilizing the mind, and benefiting the intellect. It is classified as a top-quality medicine in Shennong's Classic of Materia Medica. Polysaccharide is an important active ingredient in Polygala tenuifolia, which consists of several monosaccharides, including Ara, Gal, Glc, and so on. In this review, the preparation methods, structural characteristics, and biological activities of polysaccharides from Polygala tenuifolia are summarized, and the problems in the current studies are discussed to support further research, development, and utilization.

摘要

远志是一种应用历史悠久的传统中药,具有止咳、平喘、安神益智的功效。它在《神农本草经》中被列为上品。多糖是远志中的一种重要活性成分,由阿拉伯糖、半乳糖、葡萄糖等多种单糖组成。本文综述了远志多糖的制备方法、结构特征和生物活性,并讨论了当前研究中存在的问题,以支持进一步的研究、开发和利用。

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