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机器人辅助原位肾移植术:手术技术及初步结果。

Orthotopic Robot-assisted Kidney Transplantation: Surgical Technique and Preliminary Results.

机构信息

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.

出版信息

Eur Urol. 2024 Jun;85(6):556-564. doi: 10.1016/j.eururo.2024.03.037. Epub 2024 Apr 15.

Abstract

BACKGROUND AND OBJECTIVE

Orthotopic kidney transplantation (KT) has been proposed as an option for patients ineligible for heterotopic KT. In this scenario, orthotopic robot-assisted KT (oRAKT) represents a novel, minimally invasive alternative to the open approach. Here we describe the largest oRAKT series of patients, with a focus on the surgical technique, perioperative surgical outcomes, and functional results.

METHODS

We queried prospectively maintained databases from three referral centers to identify patients who underwent oRAKT and evaluated surgical and functional outcomes.

KEY FINDINGS AND LIMITATIONS

Overall, 16 oRAKT procedures were performed between January 2020 and August 2023. These involved four donors after cardiovascular death, five donors after brain death, and seven living donors. All oRAKT procedures were carried out in the left renal fossa. The indication for oRAKT was extensive calcification of the external iliac vessels (100%), frequently associated with prior KT (31%). The median operative time was 295 min (interquartile range [IQR] 268-360) and the median rewarming time 48 min (IQR 40-54). Conversion to open surgery occurred in two cases (12%), and delayed graft function was observed in two cases (12%). Postoperative complications occurred in 11 patients (69%) and three (18%) experienced Clavien-Dindo grade >II complications. At median follow-up of 9 mo (IQR 7-17), 14 patients had a functioning graft and median creatinine of 1.49 mg/dl (IQR 1.36-1.72).

CONCLUSIONS AND CLINICAL IMPLICATIONS

Although oRAKT is a challenging procedure, it represents a feasible option for individuals ineligible for heterotopic KT and yields favorable perioperative and mid-term functional outcomes.

PATIENT SUMMARY

We evaluated outcomes of orthotopic robot-assisted kidney transplantation (KT), in which the native kidney is removed and the donor kidney is transplanted into its place, in patients who are not eligible for heterotopic KT, in which the native kidney is left in place and the donor kidney is transplanted into a new location. We found that robot-assisted surgery is a safe and feasible alternative to traditional open surgery for orthotopic KT.

摘要

背景与目的

对于不适合异位肾移植(KT)的患者,原位肾移植(KT)已被提议作为一种选择。在这种情况下,机器人辅助原位 KT(oRAKT)是一种新颖的微创替代开放手术的方法。本文描述了最大的 oRAKT 患者系列,重点介绍手术技术、围手术期手术结果和功能结果。

方法

我们从三个转诊中心的前瞻性维护数据库中查询,以确定接受 oRAKT 的患者,并评估手术和功能结果。

主要发现和局限性

总体而言,2020 年 1 月至 2023 年 8 月期间共进行了 16 例 oRAKT 手术。这些手术涉及 4 例心脏死亡后供体、5 例脑死亡后供体和 7 例活体供体。所有 oRAKT 手术均在左肾窝进行。oRAKT 的适应证为髂外血管广泛钙化(100%),常伴有既往 KT(31%)。中位手术时间为 295 分钟(四分位距 [IQR] 268-360),中位复温时间为 48 分钟(IQR 40-54)。2 例(12%)转为开放手术,2 例(12%)发生延迟肾功能。11 例(69%)患者术后发生并发症,3 例(18%)患者发生 Clavien-Dindo 分级>Ⅱ级并发症。中位随访 9 个月(IQR 7-17)时,14 例患者有功能移植物,中位肌酐 1.49mg/dl(IQR 1.36-1.72)。

结论和临床意义

尽管 oRAKT 是一项具有挑战性的手术,但对于不适合异位 KT 的患者来说,它是一种可行的选择,并且具有良好的围手术期和中期功能结果。

患者总结

我们评估了不适合异位肾移植(KT)的患者的原位机器人辅助肾移植(oRAKT)的结果,在这种情况下,将去除原生肾脏并将供体肾脏移植到其位置,而不是将原生肾脏留在原位并将供体肾脏移植到新位置。我们发现,机器人辅助手术是一种安全且可行的替代传统开放手术的方法,用于原位 KT。

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