Abebe Ayanaw Dinku, Assefa Muluneh, Belete Debaka, Ferede Getachew
Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Infect Drug Resist. 2024 Apr 11;17:1407-1417. doi: 10.2147/IDR.S455562. eCollection 2024.
Globally, viral hepatitis is a leading cause of death and is highly prevalent in Ethiopia. Military personnel are more vulnerable to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, and there are no data on such populations in the study area. Therefore, this study aimed to determine the seroprevalence of HBV and HCV infections and their associated factors among military personnel in military camps in Central Gondar, Ethiopia.
This institutional-based cross-sectional study was conducted with 277 military personnel from April to August 2022 at military camps in Central Gondar, Ethiopia. A systematic random sampling technique was used to select the study participants. Sociodemographic and other relevant data were collected using a structured questionnaire. Five milliliters of venous blood were collected using a vacutainer tube and tested for hepatitis B surface antigens and anti-hepatitis C virus antibodies using an enzyme-linked immunosorbent assay. Data were analyzed using STATA version 14 software and logistic regression models were used to determine the association between HBV/HCV infection and risk factors.
Out of 277 participants, the overall seroprevalence of HBV and HCV infections was 19 (6.9%) and 9 (3.3%), respectively. The rate of HBV and HCV co-infection was 2 (0.7%). Having multiple sexual partners (p = 0.048), frequent alcohol use (p = 0.034), hospitalization (p = 0.014), and history of receiving injections from traditional practitioners (p = 0.040) were significant predictors of HBV infection. In contrast, a history of blood transfusion (p = 0.048) and sexually transmitted infections (p = 0.039) were significant risk factors for HCV infection.
An intermediate prevalence of HBV and HCV infections was observed among the military personnel. Continuous screening, adherence to healthcare service guidelines, and strengthening of vaccination are crucial for preventing HBV and HCV infections.
在全球范围内，病毒性肝炎是主要的死亡原因，在埃塞俄比亚高度流行。军事人员更容易感染乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV），而研究区域内尚无此类人群的数据。因此，本研究旨在确定埃塞俄比亚贡德尔中部军营中军事人员HBV和HCV感染的血清流行率及其相关因素。
本基于机构的横断面研究于2022年4月至8月在埃塞俄比亚贡德尔中部的军营中对277名军事人员进行。采用系统随机抽样技术选择研究参与者。使用结构化问卷收集社会人口学和其他相关数据。使用真空采血管采集5毫升静脉血，并采用酶联免疫吸附测定法检测乙型肝炎表面抗原和抗丙型肝炎病毒抗体。使用STATA 14版软件进行数据分析，并使用逻辑回归模型确定HBV/HCV感染与危险因素之间的关联。
在277名参与者中，HBV和HCV感染的总体血清流行率分别为19例（6.9%）和9例（3.3%）。HBV和HCV合并感染率为2例（0.7%）。有多个性伴侣（p = 0.048）、频繁饮酒（p = 0.034）、住院（p = 0.014）以及有从传统从业者处接受注射的病史（p = 0.040）是HBV感染的重要预测因素。相比之下，输血史（p =
