Riaz Maryam, Jha Swastika
Department of Internal Medicine, Baylor Scott and White Medical Center, Temple, Texas, USA.
Central Texas Veterans Affairs Hospital, Temple, Texas, USA.
Proc (Bayl Univ Med Cent). 2024 Mar 19;37(3):489-492. doi: 10.1080/08998280.2024.2325322. eCollection 2024.
Sarcoidosis is a multisystem inflammatory condition presenting with the formation of noncaseating granulomas. These granulomas can be found in nearly every organ of the body, but in 90% of cases the lungs are involved. Osseous manifestations are seen in only 3% to 13% of cases and are typically seen alongside the more common pulmonary manifestations. These lesions can be misdiagnosed as metastatic cancer so biopsy, along with clinical correlation and exclusion of other diseases, is necessary to make the diagnosis. Most patients with primary osseous sarcoidosis remain asymptomatic but routine monitoring is necessary to identify progression to lesion growth, cardiac manifestations, and respiratory involvement.
结节病是一种多系统炎症性疾病，表现为非干酪样肉芽肿的形成。这些肉芽肿几乎可在身体的每个器官中发现，但在90%的病例中肺部会受累。骨表现仅见于3%至13%的病例，通常与更常见的肺部表现同时出现。这些病变可能被误诊为转移性癌症，因此活检以及临床关联和排除其他疾病对于做出诊断是必要的。大多数原发性骨结节病患者无症状，但需要进行常规监测以确定病变生长、心脏表现和呼吸系统受累的进展情况。
