Marino Andrea, Cacciaguerra Giovanni, Spampinato Serena, Palermo Monica, Biasco Arturo, Liotta Emanuele, Cocuzza Salvatore, Venanzi Rullo Emmanuele, Nunnari Giuseppe, Pavone Piero
Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Catania, ARNAS Garibaldi Hospital, I-95122 Catania, Italy.
Department of Clinical and Experimental Medicine, Section of Paediatrics and Child Neuropsychiatry, School of Specialization in Paediatrics, University of Catania, I-95124 Catania, Italy.
Biomed Rep. 2024 Mar 27;20(5):83. doi: 10.3892/br.2024.1771. eCollection 2024 May.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection usually affects the respiratory system; however, a number of atypical manifestations of this disease have also been reported, especially in children. The present study reports a case of a 12-year-old presenting with right unilateral parotitis and sialadenitis and SARS-CoV-2 infection. The young patient, after a 3-day history of fever, was brought to our clinic (Polyclinic University Hospital 'G. Rodolico', Catania, Italy) for the sudden onset of unilateral parotitis accompanied by sialadenitis and hyperaemia of the skin, which was tender to touch. The SARS-CoV-2 molecular swab was positive; the ultrasound of the affected region showed an increase in the volume of the parotid and sublingual gland and reactive lymph nodes compatible with parotitis and sialadenitis. This case suggests that, in the present Coronavirus disease 2019 pandemic, SARS-CoV-2 should be included in the differential diagnosis of parotitis and sialadenitis along with mumps and flue. Notably, a respiratory panel and serology for other potential causes are needed in case of parotitis-like disease.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染通常影响呼吸系统；然而，该疾病的一些非典型表现也有报道，尤其是在儿童中。本研究报告了一例12岁儿童，表现为右侧单侧腮腺炎、涎腺炎及SARS-CoV-2感染。该年轻患者在发热3天后，因突然出现单侧腮腺炎伴涎腺炎及皮肤充血、触痛而被送至我们的诊所（意大利卡塔尼亚的“G. Rodolico”综合大学医院）。SARS-CoV-2分子拭子检测呈阳性；受影响区域的超声显示腮腺和舌下腺体积增大以及与腮腺炎和涎腺炎相符的反应性淋巴结。该病例表明，在当前的2019冠状病毒病大流行中，SARS-CoV-2应与腮腺炎和流感一起纳入腮腺炎和涎腺炎的鉴别诊断。值得注意的是，在出现类似腮腺炎疾病的情况下，需要进行呼吸道检测及针对其他潜在病因的血清学检测。
