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低至中度心脏手术风险患者的一期或二期择期冠状动脉搭桥手术及腹主动脉瘤开放修复术。

One-stage or two-stage elective coronary artery bypass graft surgery and abdominal aortic aneurysm open repair in low and moderate cardiac surgical risk patients.

作者信息

Gómez-Galán Sebastián, Velandia-Sánchez Alejandro, Corso-Ramírez Julián M, Polanía-Sandoval Camilo A, Florez-Amaya Paula C, Ortigoza-Espitia Sergio A, Suarez-Vásquez Sofía N, Sanabria-Arévalo Lina M, Barrera-Carvajal Juan G, Camacho-Mackenzie Jaime

机构信息

Department of Cardiovascular Surgery, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.

Vascular and Endovascular Surgery Research Group, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.

出版信息

Vascular. 2025 Apr;33(2):269-277. doi: 10.1177/17085381241247881. Epub 2024 Apr 17.

Abstract

ObjectivesCoronary artery disease (CAD) and abdominal aortic aneurysm (AAA) are common arterial pathologies that might occur simultaneously; however, there is not enough evidence about the optimal strategy for patients with concomitant indications of coronary artery bypass grafting (CABG) and open repair of the AAA (AAOR). This study aims to present the outcomes in low and moderate cardiac surgical risk patients who underwent one-stage or two-stage elective CABG and AAOR in a middle-income country.MethodsAn observational, retrospective case series study was conducted. Patients who had low and moderate cardiac surgical risk (less than 8% mortality risk on the STS score) and had the concomitant indication for CABG and AAOR between December 2005 and August 2021 were included. Patients were assigned to one of three strategies: Group 1 underwent one-stage surgery for CABG and AAOR, Group 2 underwent two-stage surgery within the same in-patient stay, and Group 3 underwent two-stage surgery in a new in-patient stay within 6 months.ResultsTwenty seven, patients with simultaneous requirements of CABG and AAOR were identified, with a mean age of 69.5 ± 6.1 years and 92.6% were male. The most common comorbidities were hypertension at 77.8% and dyslipidemia at 55.6%. The average mortality risk calculated by the STS score was 2.09% ± 1.53%. In Group 1 ( = 9), 1/9 had in-hospital mortality and no reinterventions were needed. In Group 2 ( = 10), 1/10 had in-hospital mortality, and the most common postoperative complication was acute kidney injury 2/10. Furthermore, 2/10 required a reintervention. In Group 3 ( = 8), no in-hospital mortality was present, however, complications such as sepsis, atrial fibrillation, and acute kidney injury occurred in 2/8 patients each, and 2/8 required a reintervention.ConclusionPatients with CAD and AAA that need a concomitant surgical correction with CABG and an AAOR are uncommon in contemporary practice, given the advances in endovascular therapy. When indicated, one-stage surgery can be performed in patients with low cardiac surgical risk, proper patient selection plays a fundamental role and might be performed in experienced centers. However, two-staged surgeries at the same or different inpatient stay may be considered for asymptomatic AAA with close monitoring during the postoperative period. These findings can hold significance for addressing sociodemographic barriers in low and middle-income countries. More robust and extensive studies are needed to make clear comparisons between the different strategies.

摘要

目的

冠状动脉疾病(CAD)和腹主动脉瘤(AAA)是常见的动脉病变,可能同时发生;然而,对于同时有冠状动脉旁路移植术(CABG)和腹主动脉瘤开放修复术(AAOR)指征的患者,尚无足够证据支持最佳治疗策略。本研究旨在呈现中等收入国家中低心脏手术风险患者接受一期或二期择期CABG和AAOR的结果。

方法

进行了一项观察性回顾性病例系列研究。纳入2005年12月至2021年8月期间心脏手术风险低至中等(STS评分死亡风险低于8%)且同时有CABG和AAOR指征的患者。患者被分配至三种策略之一:第1组接受CABG和AAOR一期手术,第2组在同一住院期间接受二期手术,第3组在6个月内的新住院期间接受二期手术。

结果

共确定27例同时需要CABG和AAOR的患者,平均年龄69.5±6.1岁,92.6%为男性。最常见的合并症为高血压(77.8%)和血脂异常(55.6%)。通过STS评分计算的平均死亡风险为2.09%±1.53%。第1组(n = 9)中,1/9有院内死亡,无需再次干预。第2组(n = 10)中,1/10有院内死亡,最常见的术后并发症是急性肾损伤(2/10)。此外,2/10需要再次干预。第3组(n = 8)无院内死亡,但2/8患者发生了脓毒症、心房颤动和急性肾损伤等并发症,2/8需要再次干预。

结论

鉴于血管内治疗的进展,在当代实践中,同时需要CAD和AAA手术矫正以及CABG和AAOR的患者并不常见。如有指征,心脏手术风险低的患者可进行一期手术,合适的患者选择起着关键作用,且可能在有经验的中心进行。然而,对于无症状AAA,可考虑在同一或不同住院期间进行二期手术,并在术后密切监测。这些发现对于解决低收入和中等收入国家的社会人口学障碍可能具有重要意义。需要更有力和广泛的研究来明确不同策略之间的比较。

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