Antimicrobial secondary metabolites and antioxidant activities of fungal endophytes associated with (L.) Desf. (Nabq) leaves.

A total of 20 endophytic fungi were isolated (ZSEFL1-ZSEFL20) from (L.) Desf. (Nabq) leaves. Four isolates A2/ZSEFL2, , D/ZSEFL14, , E/ZSEFL15, , and S/ZSEFL19, were found to show the most promising antimicrobial activities either in plug or disc diffusion screening assays against Gram-positive, Gram-negative bacteria and pathogenic fungi. Antimicrobial activity was tested against ATCC 27853, ATCC 29213, ATCC 14764, e ATCC 700603, ATCC 10231, and ATCC417. antioxidant activity assay was conducted using the ABTS [2,2'-Azino-bis (3-Ethylbenzthiazoline-6-Sulfonic Acid)] free radical scavenging method. EtOAc extracts of all isolated endophytic fungi showed antioxidant activities. This study would be one of the first reports to measure the antioxidant activity of (L.) Desf. endophytic fungi. Therefore, these isolated endophytic fungi can provide additional information for medicinal sources of natural antioxidants and antimicrobial agents.