Önal Uğur, Akalın Halis
Department of Infectious Diseases and Clinical Microbiology, Uludağ University School of Medicine, Bursa, Turkey.
Infect Dis Clin Microbiol. 2023 Jun 23;5(2):82-93. doi: 10.36519/idcm.2023.214. eCollection 2023 Jun.
This study aimed to identify opportunistic infections among human immunodeficiency virus (HIV) infected patients in Turkey. Therefore, we conducted a systematic literature review of the studies published up to October 1, 2022, in the Pubmed, Web of Science (WoS), and ULAKBİM TR Dizin databases. We searched for medical subject headings (MeSH) terms of (HIV) OR (AIDS) OR (human immunodeficiency virus) AND (opportunistic infections) AND (Turkey). Fifty-five studies in Pubmed, 68 in WoS, and 212 in ULAKBİM TR Dizin were listed with these keywords. After removing duplicated studies, we included 22 original articles, two poster presentations, one short communication, one letter to the editor, and 17 case reports/series. Out of 1582 patients, we defined 788 patients (49.8%) as late presenters. In addition, we detected tuberculosis (286, 5.5%), candidal infections (207, 4%), and pneumonia (PCP) (113, 2.1%) as the most frequent opportunistic infections. According to our analysis, late presentation is a major problem in our country, and more screening and sensitization campaigns should be carried out to ensure early diagnosis and earlier care of patients.
本研究旨在确定土耳其人类免疫缺陷病毒（HIV）感染患者中的机会性感染情况。因此，我们对截至2022年10月1日在PubMed、科学网（WoS）和ULAKBİM TR Dizin数据库中发表的研究进行了系统的文献综述。我们搜索了医学主题词（MeSH）：（HIV）或（艾滋病）或（人类免疫缺陷病毒）以及（机会性感染）和（土耳其）。使用这些关键词在PubMed中列出了55项研究，在WoS中列出了68项，在ULAKBİM TR Dizin中列出了212项。在去除重复研究后，我们纳入了22篇原创文章、两篇海报展示、一篇简短通讯、一封致编辑的信以及17例病例报告/系列。在1582名患者中，我们将788名患者（49.8%）定义为晚期就诊者。此外，我们检测到结核病（286例，5.5%）、念珠菌感染（207例，4%）和肺炎（肺孢子菌肺炎，PCP）（113例，2.1%）是最常见的机会性感染。根据我们的分析，晚期就诊是我国的一个主要问题，应开展更多的筛查和宣传活动，以确保患者得到早期诊断和更早的治疗。
