Marmin Agathe, Dufour Nina, Facca Sybille, Catheline Stefan, Chatelin Simon, Nahas Amir
Université de Strasbourg, CNRS, ICube, UMR 7357, 67000 Strasbourg, France.
Department of Hand Surgery, SOS hand, University Hospital of Strasbourg, FMTS, 1 avenue Molière, 67000 Strasbourg, France.
Biomed Opt Express. 2024 Mar 26;15(4):2622-2635. doi: 10.1364/BOE.516166. eCollection 2024 Apr 1.
Elastography contrast imaging has great potential for the detection and characterization of abnormalities in soft biological tissues to help physicians in diagnosis. Transient shear-waves elastography has notably shown promising results for a range of clinical applications. In biological soft tissues such as muscle, high mechanical anisotropy implies different stiffness estimations depending on the direction of the measurement. In this study, we propose the evolution of a noise-correlation elastography approach for in-plane anisotropy mapping. This method is shown to retrieve anisotropy from simulation images before being validated on agarose anisotropic tissue-mimicking phantoms, and the first results on biological fibrous tissues are presented.
弹性成像对比成像在检测和表征生物软组织异常方面具有巨大潜力,有助于医生进行诊断。瞬态剪切波弹性成像在一系列临床应用中已显著显示出有前景的结果。在诸如肌肉等生物软组织中,高机械各向异性意味着根据测量方向会有不同的硬度估计值。在本研究中,我们提出了一种用于平面内各向异性映射的噪声相关弹性成像方法的改进。该方法在琼脂糖各向异性组织模拟体模上得到验证之前,先从模拟图像中获取各向异性,并展示了在生物纤维组织上的初步结果。