Casentini L, Visonà A, Colombo F, Pansa V S, Pozza F, Benedetti A
Tumori. 1985 Aug 31;71(4):391-6. doi: 10.1177/030089168507100413.
Sarcoma as a second malignant neoplasm following radiotherapy is a rare occurrence in childhood. A case of osteogenic osteosarcoma of temporoparietal bone that developed 56 months after irradiation for a cerebellar astrocytoma in a 10-year-old child is reported and the pertinent literature is briefly reviewed. The possibility of an association (in the same patient) between these two rather uncommon lesions is extremely unlikely. Therefore, it is possible that radiotherapy played a role in the induction of the sarcoma. The indolent course of the latter is stressed.
肉瘤作为放疗后的第二种恶性肿瘤在儿童中很少见。本文报告了一例10岁儿童在接受小脑星形细胞瘤放疗56个月后发生的颞顶骨成骨性骨肉瘤病例,并对相关文献进行了简要回顾。这两种相当罕见的病变(在同一患者中)之间存在关联的可能性极小。因此,放疗有可能在肉瘤的诱发中起了作用。文中强调了后者病程进展缓慢。