Sugita Y, Shigemori M, Miyagi J, Ochiai S, Lee S, Watanabe T, Abe H, Morimatsu M
Department of Neurosurgery, Kurume University School of Medicine, Fukuoka.
Neurol Med Chir (Tokyo). 1992 Jan;32(1):32-5. doi: 10.2176/nmc.32.32.
The authors report a case of radiation-induced calvarial osteosarcoma. A 58-year-old female received subtotal removal of the pituitary adenoma and 5000 rads postoperative irradiation. Seven years later, an osteoblastic osteosarcoma occurred in the frontotemporal region. She received total tumor removal and chemotherapy. However, computed tomography subsequently revealed multiple small lesions at the margin of the bone flap. A chest x-ray film demonstrated lung metastasis. Local recurrence and lung metastasis require careful attention in radiation-induced osteosarcoma patients.
作者报告了一例放射性诱发的颅骨骨肉瘤病例。一名58岁女性接受了垂体腺瘤次全切除及术后5000拉德的放疗。七年后，额颞部发生了成骨性骨肉瘤。她接受了肿瘤全切及化疗。然而，计算机断层扫描随后显示骨瓣边缘有多个小病灶。胸部X光片显示有肺转移。放射性诱发骨肉瘤患者的局部复发和肺转移需要密切关注。
