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在局部麻醉下经计算机断层扫描引导的经皮球囊压迫治疗复发性三叉神经痛的疗效和安全性:一项前瞻性研究。

Efficacy and Safety of Computed Tomography-Guided Percutaneous Balloon Compression under Local Anesthesia for Recurrent Trigeminal Neuralgia: A Prospective Study.

机构信息

Department of Pain, Second Hospital of Hebei Medical University, 215 Hepingxi Road, Shijiazhuang, Hebei 050000, China.

Department of Neurology, Second Hospital of Hebei Medical University, 215 Hepingxi Road, Shijiazhuang, Hebei 050000, China.

出版信息

Pain Res Manag. 2024 Apr 9;2024:8885274. doi: 10.1155/2024/8885274. eCollection 2024.

DOI:10.1155/2024/8885274
PMID:38633819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11022504/
Abstract

PURPOSE

There are several ways to treat trigeminal neuralgia (TN); however, TN may recur after treatment. This study investigated the efficacy and safety of computed tomography (CT)-guided percutaneous balloon compression (PBC) under local anesthesia for treatment of recurrent trigeminal neuralgia. . This is a prospective and nonrandomized controlled clinical study. Forty-eight patients with classical TN were scheduled to undergo PBC surgery at the pain department of our institution between January 2021 and June 2021. The patients were prospectively divided into an initial onset group, A (21 cases), and a recurrence group, B (27 cases). All surgeries were performed with CT guidance and under local anesthesia. Postoperative complications were also observed. Pain was assessed using the visual analog scale (VAS) and Barrow Neurological Institute (BNI) scale. Efficacy indices were evaluated at 3, 6, 12, and 18 months after surgery.

RESULTS

All participants reported complete pain relief at discharge. After 18 months of follow-up, the total effective rate of pain control was 89.5% (group A, 90.5%; group B, 88.8%). There was no significant difference in the BNI scores between the two groups before and after treatment. All patients had hypoesthesia on the affected side, and no severe complications such as diplopia, blindness, intracranial hemorrhage, or intracranial infection occurred.

CONCLUSIONS

CT-guided PBC under local anesthesia is safe and effective for the treatment of recurrent TN and thus acts as an effective alternative for geriatric patients and those with high-risk factors.

摘要

目的

有几种方法可以治疗三叉神经痛(TN);然而,TN 治疗后可能会复发。本研究调查了在局部麻醉下 CT 引导经皮球囊压迫(PBC)治疗复发性三叉神经痛的疗效和安全性。这是一项前瞻性、非随机对照的临床研究。2021 年 1 月至 2021 年 6 月,我们机构疼痛科计划对 48 例经典型 TN 患者进行 PBC 手术。患者前瞻性地分为初发组(A 组,21 例)和复发组(B 组,27 例)。所有手术均在 CT 引导和局部麻醉下进行。还观察了术后并发症。疼痛采用视觉模拟评分(VAS)和巴罗神经研究所(BNI)量表评估。术后 3、6、12 和 18 个月评估疗效指标。

结果

所有患者出院时均报告完全缓解疼痛。随访 18 个月后,疼痛控制的总有效率为 89.5%(A 组为 90.5%,B 组为 88.8%)。治疗前后两组 BNI 评分无显著差异。所有患者患侧均出现感觉迟钝,无复视、失明、颅内出血或颅内感染等严重并发症。

结论

在局部麻醉下 CT 引导 PBC 治疗复发性 TN 安全有效,是老年患者和高危患者的有效替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/f3c63514ab78/PRM2024-8885274.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/de7c18664dbe/PRM2024-8885274.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/b83e2056f268/PRM2024-8885274.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/a2197109d85b/PRM2024-8885274.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/f3c63514ab78/PRM2024-8885274.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/de7c18664dbe/PRM2024-8885274.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/b83e2056f268/PRM2024-8885274.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/a2197109d85b/PRM2024-8885274.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/11022504/f3c63514ab78/PRM2024-8885274.004.jpg

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