Department of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Japan.
Department of Surgery, Ehime Prefectural Central Hospital, Matsuyama, Japan.
J Gastroenterol Hepatol. 2024 Aug;39(8):1528-1534. doi: 10.1111/jgh.16557. Epub 2024 Apr 18.
Rapidly aging societies have become a major issue worldwide including Japan. This study aimed to elucidate relative changes in the characteristics of inpatients in Japan related to this issue.
A total of 23 835 Japanese inpatients treated from 2010 to 2021 were enrolled (2010-2013, period I; 2014-2017, period II; 2018-2021, period III). Changes in clinical features were retrospectively analyzed based on ICD-10 diagnosis data.
The percentage of patients aged over 75 years increased over time (period I, 38.0%; II, 39.5%, III, 41.4%). Emergency admissions comprised 27.5% of all in period I, which increased to 43.2% in period II and again to 44.5% in period III (P < 0.001). In period I, gastrointestinal disease, liver disease, pancreatic-biliary disease, and other disease types were noted in 47.4%, 29.5%, 19.2%, and 3.9%, respectively, while those values were 44.0%, 18.0%, 33.9%, and 4.1%, respectively, in period III (P < 0.001). The frequency of liver disease decreased by approximately 0.6-fold from periods I to III, while that of biliary-pancreatic disease increased by approximately 1.8-fold during that time. Both percentage and actual numbers of patients with biliary-pancreatic disease increased during the examined periods. Analysis of changes in the proportion of organs affected by malignancy during periods I, II, and III showed a marked increase in cases of biliary-pancreatic malignancy (11.6%, 19.5%, 26.6%, respectively) (P < 0.001).
In association with the rapidly aging Japanese society, there has been an increasing frequency of biliary-pancreatic disease cases requiring hospitalization for treatment in the west Japan region of Shikoku.
人口快速老龄化已成为全球范围内的一个主要问题，包括日本。本研究旨在阐明与这一问题相关的日本住院患者特征的相对变化。
共纳入 2010 年至 2021 年期间治疗的 23835 名日本住院患者（2010-2013 年，第 I 期；2014-2017 年，第 II 期；2018-2021 年，第 III 期）。基于 ICD-10 诊断数据，回顾性分析临床特征变化。
患者年龄在 75 岁以上的比例随时间推移而增加（第 I 期 38.0%，第 II 期 39.5%，第 III 期 41.4%）。第 I 期所有住院患者中急诊入院占 27.5%，第 II 期增至 43.2%，第 III 期再次增至 44.5%（P<0.001）。第 I 期，胃肠道疾病、肝病、胰胆疾病和其他疾病类型分别占 47.4%、29.5%、19.2%和 3.9%，而第 III 期分别为 44.0%、18.0%、33.9%和 4.1%（P<0.001）。从第 I 期到第 III 期，肝病的频率下降了约 0.6 倍，而同期胰胆疾病的频率增加了约 1.8 倍。在此期间，胰胆疾病患者的比例和实际数量均有所增加。分析第 I、II 和 III 期恶性肿瘤受累器官比例的变化，显示胰胆恶性肿瘤的病例明显增加（分别为 11.6%、19.5%、26.6%）（P<0.001）。
与日本人口快速老龄化相关，在日本四国地区西部地区，因胰胆疾病住院治疗的病例频率增加。
