Larsen M J, Jensen S J
Arch Oral Biol. 1985;30(6):471-5. doi: 10.1016/0003-9969(85)90092-5.
Various amounts of enamel-apatite powder were suspended in an acetate buffer (pH 4.5) containing sufficient fluoride to give molar ratios of fluoride/apatite from zero to unity. The suspensions were equilibrated at 20 degrees C for periods between 4h and 1 year, with continuous gentle stirring. Solubility studies showed dissolution of hydroxyapatite, formation and re-dissolution of calcium fluoride and formation of fluorapatite. The amount of mineral dissolved was low during the fluorapatite formation and increased by a factor of approx. 10 as equilibrium was approached. The fluoride content of the solid apatite, which ranged from 0.1 to 70 mol% fluorapatite, only influenced the solubility slightly, whereas the fluoride content of the bathing solution had a large effect. X-ray diffraction showed a linear correlation between the fluoride content and the a-axis of the apatite.
将不同量的釉质磷灰石粉末悬浮于含有足够氟化物的醋酸盐缓冲液（pH 4.5）中，以使氟化物/磷灰石的摩尔比从零到一。将悬浮液在20℃下平衡4小时至1年，期间持续温和搅拌。溶解度研究表明，羟基磷灰石溶解，氟化钙形成并重新溶解，氟磷灰石形成。在氟磷灰石形成过程中溶解的矿物质含量较低，接近平衡时增加约10倍。固体磷灰石中的氟含量范围为0.1至70摩尔%氟磷灰石，仅对溶解度有轻微影响，而浴液中的氟含量则有很大影响。X射线衍射显示氟含量与磷灰石的a轴之间存在线性关系。
