Laboratory of Ecological Immunology of Aquatic Organisms, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Leninsky Ave, 14, Moscow 119991, Russia.
Laboratory of Ecological Immunology of Aquatic Organisms, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Leninsky Ave, 14, Moscow 119991, Russia.
Comp Biochem Physiol B Biochem Mol Biol. 2024 Aug-Sep;273:110980. doi: 10.1016/j.cbpb.2024.110980. Epub 2024 Apr 16.
Boring sponge infection affects growth, development and reduces the soft tissue weight of oysters. In this study, we investigated the effects of boring sponge on the activity of three antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GP)) in the mantle, and the production of reactive oxygen species (ROS) and potential genotoxicity in hemocytes of the Pacific oyster Magallana gigas. Our results showed a significant increase in ROS production and DNA damage in hemocytes. Notably, the activity of SOD, CAT, and GP in the mantle was not significantly affected by boring sponge infection. Collectively, these results suggest that sponge invasion may cause oxidative stress in Pacific oyster hemocytes through ROS overproduction.
海绵窦感染会影响牡蛎的生长、发育，降低其软组织重量。本研究调查了海绵窦感染对太平洋牡蛎（Magallana gigas）外套膜三种抗氧化酶（超氧化物歧化酶（SOD）、过氧化氢酶（CAT）和谷胱甘肽过氧化物酶（GP））活性、血细胞中活性氧（ROS）产生和潜在遗传毒性的影响。结果显示，血细胞中 ROS 产生和 DNA 损伤显著增加。值得注意的是，海绵窦感染对外套膜中 SOD、CAT 和 GP 的活性没有显著影响。综上所述，这些结果表明，海绵窦感染可能通过 ROS 过度产生导致太平洋牡蛎血细胞发生氧化应激。
