Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Young Researchers and Elite Club, Islamic Azad University of Karaj, Karaj, Iran.
Front Public Health. 2024 Apr 4;12:1322072. doi: 10.3389/fpubh.2024.1322072. eCollection 2024.
Diabetes mellitus (DM) poses a significant threat to public health, and the anticipated surge of over 100% in the age-standardized prevalence of type 2 diabetes in Iran between 2021 and 2050 underscores the pressing need for focused attention. The rationale for estimating the prevalence of type 2 diabetes in Iran becomes even more compelling when considering the potential cascading effects on the healthcare system, quality of life, and economic burden. The aim of this study was to estimate the prevalence and trends of DM from 1996 to 2023 in the Islamic Republic of Iran.
Up to July 2023, without deadlines, the search for appropriate articles in Persian and English. Iranian sources including SID, Magiran, and Element were included in the databases, along with foreign ones like PubMed/MEDLINE, Web of Science, Science Direct, Embase, Scopus, ProQuest, and Google Scholar. Using the JBI quality checklist, the study's level of quality was evaluated. Version 14 of STATA was used to carry out the statistical analysis. The Dersimonian and Liard random-effects models were used because of heterogeneity. To investigate the causes of heterogeneity, subgroup analysis and univariate meta-regression were utilized. Sensitivity analysis was then carried out to see how each study's findings affected the final findings. The prevalence pattern over time was also followed using cumulative meta-analysis.
There were 53 studies in all, with a combined sample size of 1,244,896 people. Men were predicted to have a type 2 diabetes prevalence of 10.80% (95% CI: 9.1-12.4), while women were assessed to have a prevalence of 13.4% (95% CI: 11.6-15.3). Additionally, the prevalence of diabetes was much higher in the 55-64 age group, coming in at 21.7% (95% CI: 17.5-25.0). The anticipated prevalence of diabetes was 7.08% for 1988 to 2002, 9.05% for 2003 to 2007, 9.14% for 2008 to 2012, 15.0% for 2013 to 2017, and 13.40% for 2018 to 2023, among other time periods. Geographically, type 2 diabetes was most prevalent in Khuzestan (15.3%), followed by Razavi Khorasan (14.4%), Qazvin (14.3%), and Yazd (12.6%).
The prevalence of type 2 diabetes was estimated at 10.8%, highlighting variations across gender, age groups, and geographic regions that underscore the necessity for specific interventions. These findings advocate for proactive measures, including tailored screening and lifestyle modification programs. The notable temporal increase from 2013 to 2017 signals the need for policymakers and healthcare practitioners to develop effective strategies, anticipating and addressing the potential future burden on the healthcare system.
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023437506, identifier: CRD42023437506.
糖尿病（DM）对公众健康构成重大威胁，预计 2021 年至 2050 年期间伊朗 2 型糖尿病年龄标准化患病率将增长超过 100%，这突显了需要集中关注的紧迫性。考虑到对医疗保健系统、生活质量和经济负担的潜在连锁影响，估计伊朗 2 型糖尿病患病率的理由更加充分。本研究的目的是估计 1996 年至 2023 年期间伊朗伊斯兰共和国 DM 的患病率和趋势。
截至 2023 年 7 月，无截止日期，在波斯语和英语中搜索适当的文章。伊朗来源包括 SID、Magiran 和 Element，以及包括 PubMed/MEDLINE、Web of Science、Science Direct、Embase、Scopus、ProQuest 和 Google Scholar 在内的外国数据库。使用 JBI 质量检查表评估研究的质量水平。使用 STATA 版本 14 进行统计分析。由于存在异质性，使用了 Dersimonian 和 Liard 随机效应模型。为了研究异质性的原因，进行了亚组分析和单变量荟萃回归分析。然后进行敏感性分析，以了解每项研究的结果如何影响最终结果。还使用累积荟萃分析来跟踪随时间变化的患病率模式。
共有 53 项研究，总样本量为 1244896 人。预计男性 2 型糖尿病患病率为 10.80%（95%CI：9.1-12.4），而女性为 13.4%（95%CI：11.6-15.3）。此外，55-64 岁年龄组的糖尿病患病率更高，为 21.7%（95%CI：17.5-25.0）。1988 年至 2002 年期间预计糖尿病的患病率为 7.08%，2003 年至 2007 年期间为 9.05%，2008 年至 2012 年期间为 9.14%，2013 年至 2017 年期间为 15.0%，2018 年至 2023 年期间为 13.40%，以及其他时间段。从地理上看，2 型糖尿病在胡齐斯坦省最为普遍（15.3%），其次是拉扎维霍拉桑省（14.4%）、戈兹温省（14.3%）和亚兹德省（12.6%）。
估计 2 型糖尿病的患病率为 10.8%，这突显了不同性别、年龄组和地理区域之间的差异，这突出表明需要采取具体的干预措施。这些发现呼吁采取积极措施，包括量身定制的筛查和生活方式改变计划。从 2013 年到 2017 年的显著增加表明，政策制定者和医疗保健从业者需要制定有效的策略，预测和应对医疗保健系统未来可能面临的负担。
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023437506，标识符：CRD42023437506。
