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Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions?

作者信息

Rubin Rita

机构信息

Lead Senior Staff Writer, Medical News & Perspectives, JAMA.

出版信息

JAMA. 2024 May 14;331(18):1519-1521. doi: 10.1001/jama.2024.1017.

DOI:10.1001/jama.2024.1017
PMID:38639975
Abstract
摘要

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Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions?像司美格鲁肽这样的胰高血糖素样肽-1(GLP-1)受体激动剂能治疗成瘾、阿尔茨海默病及其他病症吗?
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Ann Pharmacother. 2020 May;54(5):478-485. doi: 10.1177/1060028019889064. Epub 2019 Nov 19.

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medRxiv. 2025 Aug 15:2025.08.13.25333579. doi: 10.1101/2025.08.13.25333579.
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Barriers to glucagon-like peptide-1 agonists used for obesity management among the general population in Tabuk City, Saudi Arabia, and their relation to smoking cessation and antidepressants.沙特阿拉伯塔布克市普通人群中用于肥胖管理的胰高血糖素样肽-1激动剂的使用障碍及其与戒烟和抗抑郁药的关系。
Front Pharmacol. 2025 Jul 31;16:1510554. doi: 10.3389/fphar.2025.1510554. eCollection 2025.
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Alzheimers Dement (Amst). 2025 Jun 11;17(2):e70130. doi: 10.1002/dad2.70130. eCollection 2025 Apr-Jun.
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Front Immunol. 2025 Mar 11;16:1525623. doi: 10.3389/fimmu.2025.1525623. eCollection 2025.
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