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由四羟基二硼制备四烷氧基二硼和二硼酸二醇酯的简便绿色方法

Simple and Green Preparation of Tetraalkoxydiborons and Diboron Diolates from Tetrahydroxydiboron.

作者信息

Fornwald Ryan M, Yadav Anshu, Montero Bastidas Jose R, Smith Milton R, Maleczka Robert E

机构信息

Department of Chemistry, Michigan State University, 578 South Shaw Lane, East Lansing, Michigan 48824, United States.

出版信息

J Org Chem. 2024 May 3;89(9):6048-6052. doi: 10.1021/acs.joc.3c02992. Epub 2024 Apr 19.

DOI:10.1021/acs.joc.3c02992
PMID:38640193
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11077490/
Abstract

Tetraalkoxydiborons can be easily prepared by acid-catalyzed reactions of tetrahydroxydiboron or its anhydride with trialkyl orthoformates. Addition of diols to these reaction mixtures afforded diboron diolates in high yield. In both cases, removal of volatile byproducts is all that is required for the isolation of the diboron. These methods constitute a convenient alternative to previous preparations from tetrakis (dimethylamino) diboron and tetrahydroxydiboron.

摘要

四烷氧基二硼可通过四羟基二硼或其酸酐与原甲酸三烷基酯的酸催化反应轻松制备。向这些反应混合物中加入二醇可高产率地得到二硼酸二醇酯。在这两种情况下，分离二硼所需的只是除去挥发性副产物。这些方法是以前用四（二甲氨基）二硼和四羟基二硼制备方法的便捷替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/977b0daadae8/jo3c02992_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/17089613dee3/jo3c02992_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/a234374548cf/jo3c02992_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/8893af370662/jo3c02992_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/6580048ba88a/jo3c02992_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/977b0daadae8/jo3c02992_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/17089613dee3/jo3c02992_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/a234374548cf/jo3c02992_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/8893af370662/jo3c02992_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/6580048ba88a/jo3c02992_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc5c/11077490/977b0daadae8/jo3c02992_0005.jpg

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