Handlers J P, Abrams A M, Aberle A M, Auyong T, Melrose R J
Oral Surg Oral Med Oral Pathol. 1985 Oct;60(4):382-6. doi: 10.1016/0030-4220(85)90260-9.
Since the substitution of steroids and antimalarials for irradiation in the treatment of discoid lupus erythematosus, squamous cell carcinoma arising in discoid lupus erythematosus is thought by some to be an uncommon occurrence. A review of the recent literature (subsequent to 1945) revealed fifteen cases, of which seven occurred in the lips. In one of twelve of the cases a history of irradiation was documented. In three other cases, there was no evidence of its use. We report an additional case of squamous cell carcinoma occurring in the lower lip of a 24-year-old black woman in the absence of radiation therapy. A review of the literature and a discussion of possible predisposing factors are presented.
自从在盘状红斑狼疮的治疗中用类固醇和抗疟药取代了放射治疗后，一些人认为盘状红斑狼疮中发生的鳞状细胞癌是一种罕见的情况。回顾最近的文献（1945年之后）发现了15例病例，其中7例发生在唇部。在12例病例中的1例有放射治疗的记录。在另外3例病例中，没有使用放射治疗的证据。我们报告了另外1例鳞状细胞癌病例，发生在一名24岁黑人女性的下唇，且没有接受放射治疗。本文对文献进行了回顾并讨论了可能的诱发因素。
