Hricak H, Toledo-Pereyra L H, Eyler W R, Madrazo B L, Sy G S
Radiology. 1979 Nov;133(2):443-7. doi: 10.1148/133.2.443.
Autotransplantation of the kidney was performed in seven adult mongrel dogs. A model of acute tubular necrosis (ATN) was developed by subjecting the kidney to warm ischemia (37 degrees C) for 40 to 60 minutes. Serial ultrasound examinations were performed every 12 hours until the animal died or was killed. Sonographic findings were correlated with laboratory and histological data. Throughout the course of ATN, the characteristic normal echo pattern of the kidney remained unchanged in six of seven dogs. In one animal there were changes in the renal cortex, while the medullary pyramids showed no alteration from the base-line study. This contrasts with extensive abnormalities found during rejection.
对7只成年杂种犬进行了自体肾移植。通过使肾脏在37℃下热缺血40至60分钟建立急性肾小管坏死（ATN）模型。每12小时进行一次系列超声检查，直至动物死亡或被处死。超声检查结果与实验室和组织学数据相关。在整个急性肾小管坏死过程中，7只犬中有6只肾脏的特征性正常回声模式保持不变。在1只动物中，肾皮质有变化，而髓质锥体与基线研究相比无改变。这与排斥反应期间发现的广泛异常形成对比。
