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犬模型中急性肾移植排斥反应与急性肾小管坏死的磁共振成像评估

Acute renal rejection versus acute tubular necrosis in a canine model: MR evaluation.

作者信息

Rholl K S, Lee J K, Ling D, Sicard G A, Griffith R C, Freeman M

出版信息

Radiology. 1986 Jul;160(1):113-7. doi: 10.1148/radiology.160.1.3520644.

DOI:10.1148/radiology.160.1.3520644
PMID:3520644
Abstract

Findings of magnetic resonance (MR) imaging in acute renal rejection and acute tubular necrosis (ATN) were studied in dogs. On T1-weighted images, corticomedullary differentiation was absent in kidneys undergoing acute rejection. The loss of corticomedullary differentiation in these kidneys was secondary to a decrease in the relative signal intensity of the cortex, indicating prolongation of the T1 relaxation time of the cortex. In contrast, corticomedullary differentiation was preserved on T1-weighted images of autotransplanted kidneys and kidneys with ATN. MR imaging findings correlated with changes in water content in these three groups of kidneys. Kidneys undergoing acute rejection showed a marked increase in water content compared with kidneys in the other two groups. No change in fat content was found in any group.

摘要

对犬急性肾排斥反应和急性肾小管坏死(ATN)的磁共振(MR)成像结果进行了研究。在T1加权图像上,发生急性排斥反应的肾脏中皮质髓质分界消失。这些肾脏中皮质髓质分界的消失是由于皮质相对信号强度降低所致,这表明皮质的T1弛豫时间延长。相比之下,自体移植肾和患有ATN的肾脏的T1加权图像上皮质髓质分界得以保留。MR成像结果与这三组肾脏的含水量变化相关。与其他两组的肾脏相比,发生急性排斥反应的肾脏含水量显著增加。任何一组中脂肪含量均未发现变化。

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Acute renal rejection versus acute tubular necrosis in a canine model: MR evaluation.犬模型中急性肾移植排斥反应与急性肾小管坏死的磁共振成像评估
Radiology. 1986 Jul;160(1):113-7. doi: 10.1148/radiology.160.1.3520644.
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