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骨髓采集:NMDP 骨髓联盟最佳实践白皮书。

Bone Marrow Harvest: A White Paper of Best Practices by the NMDP Marrow Alliance.

机构信息

Dana-Farber Cancer Institute, Boston, Massachusetts.

Division of Hematology, Department of Medicine, University of Washington and Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.

出版信息

Transplant Cell Ther. 2024 Jul;30(7):663-680. doi: 10.1016/j.jtct.2024.04.010. Epub 2024 Apr 18.

Abstract

Data on recent bone marrow harvest (BMH) collections from the NMDP has shown that bone marrow (BM) quality has decreased based on total nucleated cell count in the product. To ensure that quality BM products are available to all recipients, the NMDP Marrow Alliance was formed in April 2021 to increase the capability of BM collection centers to safely deliver high-quality products consistently and to identify and disseminate guidelines for performing BMH. This white paper describes the best practices for BMH as defined by the NMDP Marrow Alliance.

摘要

最近 NMDP 的骨髓采集(BMH)数据显示,基于产品中的总核细胞计数,骨髓(BM)质量已经下降。为确保所有受者都能获得高质量的 BM 产品,NMDP 骨髓联盟于 2021 年 4 月成立,旨在提高 BMH 采集中心安全持续提供高质量产品的能力,并确定和传播执行 BMH 的指南。本白皮书描述了 NMDP 骨髓联盟定义的 BMH 的最佳实践。

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