Tsushima Shingo, Maeda Toshiyuki, Nakashima Shinji, Muraki Satoshi, Sakurada Taku, Sasaki Jun, Araki Eiji
Department of Cardiovascular Surgery, Sapporo Central Hospital, Sapporo, Japan.
Kyobu Geka. 2024 Apr;77(4):316-318.
Calcified amorphous tumor (CAT), a non-neoplastic tumor, is rare. Histopathologic features are the presence of calcified nodules in an amorphous background of fibrin. CAT is reported to be associated with renal dysfunction or hemodialysis, and possibly causes cerebral embolism. We report a case of CAT diagnosed after stroke. A 58-year-old male with a 2-year history of hemodialysis was diagnosed with an acute stroke, and was treated medically. Paralysis promptly improved, but transthoracic echocardiography revealed a tumor attached to the posterior mitral leaflet and dense mitral annular calcification. To prevent embolism due to the large tumor, we performed resection of the tumor. Pathological findings showed calcifications surrounded by amorphous fibrous tissue, indicating CAT. Postoperative course was uneventful.
钙化性无定形肿瘤(CAT)是一种非肿瘤性肿瘤,较为罕见。组织病理学特征为在纤维蛋白的无定形背景中存在钙化结节。据报道,CAT与肾功能不全或血液透析有关,并且可能导致脑栓塞。我们报告一例中风后诊断出的CAT病例。一名有2年血液透析史的58岁男性被诊断为急性中风,并接受了药物治疗。瘫痪症状迅速改善,但经胸超声心动图显示一个肿瘤附着于二尖瓣后叶,且二尖瓣环有致密钙化。为防止因巨大肿瘤导致栓塞,我们进行了肿瘤切除术。病理结果显示钙化被无定形纤维组织包绕,提示为CAT。术后病程平稳。