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儿童低级别胶质瘤的瘤巢切除术。

Cylinder tumor surgery in pediatric low-grade gliomas.

机构信息

Department of Neurosurgery, "Prof. Dr. Juan P. Garrahan" Pediatric Hospital, Buenos Aires, Argentina.

Department of Neurosurgery, FLENI, Buenos Aires, Argentina.

出版信息

Childs Nerv Syst. 2024 Oct;40(10):3051-3063. doi: 10.1007/s00381-024-06417-5. Epub 2024 Apr 22.

Abstract

BACKGROUND

Periventricular pediatric low-grade gliomas (pLGG) present a surgical challenge due to their deep-seated location, accessibility, and relationship with the subcortical network connections. Minimally invasive parafascicular approaches with tubular brain retractors (port brain surgery) have emerged, in recent years, as an alternative to conventional microsurgical and endoscopic approaches for removal of periventricular tumors.

OBJECTIVES

To describe the minimally invasive approach with tubular brain retractors for periventricular pLGG, its technique, applications, safety, and efficacy.

METHODS

In this article, we describe the port brain surgery techniques for periventricular pLGG as performed in different centers, with different commercialized tubular retractor systems. Illustrative cases followed by a literature review are analyzed, with a detailed description of different approaches or techniques, comparing their advantages and disadvantages with contemporary microsurgical and endoscopic approaches.

CONCLUSIONS

The port brain surgery with micro-exoscopic vision and endoscopic assistance, for the treatment of deep-seated lesions such as periventricular pLGG, is an alternative for achieving a functionally safe-gross total or subtotal-tumor resection, obtaining adequate tissue for pathological examination. This technique could offer a new dimension for a less-invasive, safe, and effective access to deep-seated tumors, offering the possibility to lower morbidity in experienced hands.

摘要

背景

由于位置深、接近脑皮质下网络连接,儿科脑室内低度神经胶质瘤(pLGG)的手术极具挑战性。近年来,微创旁正中入路联合管状脑牵开器(端口脑外科)已成为脑室周围肿瘤切除的传统显微手术和内镜手术的替代方法。

目的

描述用于脑室周围 pLGG 的管状脑牵开器的微创入路,及其技术、应用、安全性和疗效。

方法

本文描述了在不同中心使用不同商业化管状牵开器系统进行脑室周围 pLGG 的端口脑外科技术。分析了一些病例,并进行了文献复习,详细描述了不同的入路或技术,比较了它们与当代显微和内镜手术方法的优缺点。

结论

对于脑室周围 pLGG 等深部病变的治疗,采用显微镜下微创手术和内镜辅助的端口脑外科手术是一种替代方法,可以实现功能上安全的全切除或次全切除肿瘤,并获得足够的组织进行病理检查。这种技术为微创、安全、有效的深部肿瘤治疗提供了新的维度,在经验丰富的手中降低了发病率。

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