Tenaillon A, Labrousse J, Bedicam J M, Coussa M L, Lissac J
Rev Fr Mal Respir. 1979 Jan-Feb;7(1):36-8.
This study points out that in acute respiratory distress syndrome, the positive end-expiratory pressure (PEEP) had in every case the same action on functional residual capacity and static lung compliance. However its results on PaO2, PaCO2 and circulation are often different from patient to patient according also to the different levels of PEEP. The level of optimal PEEP is that which opens the largest number of alveoli; it is better defined by the value of PaO2 on 100% oxygen than by static compliance.
本研究指出,在急性呼吸窘迫综合征中,呼气末正压(PEEP)对功能残气量和静态肺顺应性的作用在每种情况下都是相同的。然而,其对动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)和循环的影响因患者而异,这也取决于不同的PEEP水平。最佳PEEP水平是能使最大数量肺泡开放的水平;用吸入100%氧气时的PaO2值来定义比用静态顺应性来定义更好。