Labrousse J, Tenaillon A, Coussa M L, Longchal J, Lissac J
Rev Fr Mal Respir. 1979 Jan-Feb;7(1):61-3.
We defined a new optimal positive end expiratory pressure (PEEP) in the adult respiratory distress syndrome (ARDS). The optimal PEEP is the one which allows to obtain a PaO2 greater than or equal to 400 mmHg and/or an intrapulmonary shunt less than or equal to 15 p. cent, the cardiac output being held constant. 14 cases of ARDS have been treated by this method with encouraging results. The earlier optimal PEEP was applied, the more effective it was.
我们定义了成人呼吸窘迫综合征(ARDS)中的一种新的最佳呼气末正压(PEEP)。最佳PEEP是在心输出量保持恒定的情况下,能使动脉血氧分压(PaO2)大于或等于400 mmHg和/或肺内分流小于或等于15%的PEEP。14例ARDS患者采用该方法治疗,结果令人鼓舞。最佳PEEP应用得越早,效果越好。