Chan L C, Sheer D, Drysdale H C, Bevan D, Greaves M F
Br J Haematol. 1985 Nov;61(3):531-9. doi: 10.1111/j.1365-2141.1985.tb02858.x.
Monosomy 7 was the sole karyotypic abnormality seen in a case of biphenotypic leukaemia involving both the myeloid and lymphoid lineages and in a case of de novo ALL undergoing a phenotypic shift to acute myeloid leukaemia at relapse. These observations suggest that monosomy 7 can be associated with transformation of a common lymphoid-myeloid progenitor cell.
7号染色体单体是在1例涉及髓系和淋系的双表型白血病病例以及1例复发时从新发急性淋巴细胞白血病向急性髓系白血病发生表型转变的病例中观察到的唯一核型异常。这些观察结果表明，7号染色体单体可能与常见淋巴-髓系祖细胞的转化有关。
