伊朗南部法尔斯省贾赫罗姆市孕妇内脏利什曼病血清阳性率

Seroprevalence of visceral leishmaniasis among pregnant women in Jahrom city in Fars province, southern Iran.

作者信息

Sadeghi Najmeh, Mohebali Mehdi, Kakooei Zahra, Roustazadeh Abazar, Mir Hamed, Abdoli Amir, Solhjoo Kavous, Shabani Manoochehr, Shadmand Enayatollah, Taghipour Ali

机构信息

Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran.

Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Parasite Epidemiol Control. 2024 Apr 16;25:e00349. doi: 10.1016/j.parepi.2024.e00349. eCollection 2024 May.

DOI:10.1016/j.parepi.2024.e00349

PMID:38645673

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11031800/

Abstract

BACKGROUND

Visceral leishmaniasis (VL) is a public health issue in endemic countries with poor sanitation facilities. In this study, the seroprevalence rate and associated risk factors of VL were investigated during September 2020 to February 2021 in pregnant women referred to Ostad Mottahari and Peymanieh hospitals in Jahrom county, Fars province, southern Iran.

MATERIAL AND METHODS

A total of 220 serum samples of pregnant women were assessed for the presence of Anti antibodies by direct agglutination antigen (DAT). The associated risk factors were obtained using questionnaires.

RESULTS

The overall seroprevalence of VL in pregnant women was 12.72% (28/220). Considering the antibody titer, titer 1:1600 was detected in 23 samples, titer 1:3200 in 4 samples, and titer 1:6400 in one sample. All 5 women with titer >3200 had mild fever. As such, there was a statistically significant difference regarding the age (≥39 years old with value: 0.01).

CONCLUSIONS

We recommend an appropriate health education program for pregnant women and serological screening of VL before pregnancy in endemic cities. Moreover, we believed a need for more epidemiological studies for better understand the status of VL in pregnant women.

摘要