Hong Cheng-Siao, Shen Yu-Chih, Chang En-Ting, Hou Hui-Chuan, Chen Yi-Jen
Department of Human Development and Psychology, Tzu Chi University, Hualien, Taiwan.
Department of Psychiatry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Tzu Chi Med J. 2023 Dec 13;36(2):188-194. doi: 10.4103/tcmj.tcmj_128_23. eCollection 2024 Apr-Jun.
Although pulmonary rehabilitation and regular exercise have improved negative emotions and cognitive capacity within cases of chronic obstructive pulmonary disease (COPD), influence by exercise training upon different cognitive and memory functions in COPD is still controversial. This investigation aimed to assess whether cognitive performance and mental health are affected by the benefits of exercise training within cases of COPD.
This pilot investigation included thirty-three patients with Global Initiative for Chronic Obstructive Lung Disease stage ≥B. Based on the subjects' rights, all included patients could choose to join either the exercise group or the control group, according to their free will. Twelve patients were assigned to receive exercise treatment over a 2-month period, while the remaining 16 patients were assigned to the control group. Cognitive capacity outcomes were measured using the Wechsler Memory Scale-III Word List Test, Stroop task, and psychomotor vigilance task (PVT). Mood states were assessed through the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI).
Most cases demonstrated major improvement for BDI and BAI scorings post-60-day therapy. During PVT, the omission rate decreased, while the hit rate increased, indicating an improvement in attention performance. Furthermore, this investigation found a significant increase in immediate verbal and recognition memory for word-list test. However, no major performance shifts were found on Stroop analysis.
This investigation demonstrated that a 2-month exercise training program resulted in significant improvement in negative emotions, immediate memory, recognition memory, and attention.
尽管肺康复和规律运动已改善了慢性阻塞性肺疾病（COPD）患者的负面情绪和认知能力，但运动训练对COPD患者不同认知和记忆功能的影响仍存在争议。本研究旨在评估运动训练的益处是否会影响COPD患者的认知表现和心理健康。
这项初步研究纳入了33例全球慢性阻塞性肺疾病倡议组织（Global Initiative for Chronic Obstructive Lung Disease）分级≥B级的患者。根据受试者的权利，所有纳入的患者可根据自己的意愿选择加入运动组或对照组。12例患者被分配接受为期2个月的运动治疗，其余16例患者被分配到对照组。使用韦氏记忆量表第三版单词列表测试、斯特鲁普任务和心理运动警觉任务（PVT）测量认知能力结果。通过贝克抑郁量表（BDI）和贝克焦虑量表（BAI）评估情绪状态。
大多数病例在60天治疗后BDI和BAI评分有显著改善。在PVT测试中，遗漏率降低，命中率增加，表明注意力表现有所改善。此外，本研究发现单词列表测试的即时言语记忆和识别记忆有显著增加。然而在斯特鲁普分析中未发现主要的表现变化。
本研究表明，为期2个月的运动训练计划可显著改善负面情绪、即时记忆、识别记忆和注意力。
