BalajiSubramanian Sitaraman, Al-Hajri Thuraya, Satyapal Namrata, Al-Bulushi Mahdiya, Al Sheibani Salma Mohammed, Al Kalbani Faisal Khamis Mubarak, Al-Saadi Maimuna, Al Musalhi Muhanna Nasser, Al Wahshi Humaid A
Department of Radiation Oncology, The Royal Hospital, Muscat, OMN.
Department of Hematology, The Royal Hospital, Muscat, OMN.
Cureus. 2024 Mar 21;16(3):e56648. doi: 10.7759/cureus.56648. eCollection 2024 Mar.
Patients with long-standing autoimmune diseases like systemic lupus erythematosus (SLE) are at a higher risk of developing hematological malignancies. However, chronic myeloid leukemia (CML) has rarely been reported in patients with SLE. Advancements in medical diagnostics and treatment have led to the life expectancy of SLE and CML patients moving closer to that of the general population, and it is not uncommon to encounter more than one malignancy in a cancer survivor. Although squamous cell carcinoma (SCC) of the skin has been reported in CML patients, mucosal SCC of the head and neck has rarely only been reported in CML survivors. The objective of this case report is to share our experience in treating a patient with dual metachronous primary malignancies, CML, and tongue carcinoma, along with long-standing SLE, managed by a multidisciplinary team.
患有系统性红斑狼疮（SLE）等长期自身免疫性疾病的患者发生血液系统恶性肿瘤的风险更高。然而，SLE患者中很少有慢性髓系白血病（CML）的报道。医学诊断和治疗的进步使SLE和CML患者的预期寿命更接近普通人群，癌症幸存者中出现不止一种恶性肿瘤的情况并不罕见。虽然CML患者中已有皮肤鳞状细胞癌（SCC）的报道，但头颈部黏膜SCC仅在CML幸存者中很少有报道。本病例报告的目的是分享我们治疗一名患有双时相原发性恶性肿瘤（CML和舌癌）以及长期SLE的患者的经验，该患者由多学科团队管理。
