Boldrini Children's Center, Campinas, Brazil.
Oral Diagnosis Department, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Spec Care Dentist. 2021 Jul;41(4):532-538. doi: 10.1111/scd.12590. Epub 2021 Mar 23.
Pediatric hematologic malignancies present an elevated survival rate, and these survivors may experience long-term complications, including secondary malignancies. This case describes a 17-year-old female patient previously treated for acute lymphoblastic leukemia (ALL) who developed a squamous cell carcinoma (SCC, T2N0M0) of the lateral border of the tongue diagnosed during dental follow-up 2 years and 9 months after the conclusion of ALL therapy (GBTLILLA99 protocol). The patient underwent exclusive surgical resection for the tongue SCC and is free of disease 11 years after the surgery. The current case report highlights the importance of monitoring the oral health of childhood cancer survivors. As part of a multidisciplinary team, our directives include counseling to avoid carcinogenic exposures.
儿科血液系统恶性肿瘤的存活率较高，这些幸存者可能会经历长期并发症，包括继发性恶性肿瘤。本病例描述了一位 17 岁的女性患者，她曾因急性淋巴细胞白血病 (ALL) 接受治疗，在 ALL 治疗结束后 2 年零 9 个月的牙科随访中，发现舌侧缘有鳞状细胞癌 (SCC，T2N0M0)。患者因舌 SCC 接受了单纯手术切除，术后 11 年无疾病复发。本病例报告强调了监测儿童癌症幸存者口腔健康的重要性。作为多学科团队的一部分，我们的指导方针包括咨询以避免致癌物质暴露。
