Hall Ashton D, Rodriguez Laura Victoria Medina, Vearrier Jared, Patel Kavya, Hambley Bryan C, Huaman Moises A
Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
IDCases. 2024 Apr 16;36:e01968. doi: 10.1016/j.idcr.2024.e01968. eCollection 2024.
Tuberculosis (TB) is a leading infectious killer worldwide. Over two-thirds of new TB diagnoses in the United States occur among first-generation immigrants, especially within a year of migration. Hodgkin lymphoma (HL) accounts for a minority of lymphoma cases but presents similarly to disseminated or extrapulmonary TB. Clinical overlap between TB and HL increases patient risk of misdiagnosis. Concomitant presentation of both diseases is not uncommon but infrequently reported. We present a case of isoniazid-resistant TB with progressively worsening lymphadenopathy and splenomegaly despite appropriate TB treatment. The patient was diagnosed with HL following PET/CT and axillary lymph node biopsy.
结核病（TB）是全球主要的感染性致死病因。在美国，超过三分之二的新发结核病诊断病例发生在第一代移民中，尤其是在移民后的一年内。霍奇金淋巴瘤（HL）占淋巴瘤病例的少数，但临床表现与播散性或肺外结核病相似。结核病和HL之间的临床重叠增加了患者误诊的风险。两种疾病同时出现并不罕见，但报道较少。我们报告一例耐异烟肼结核病患者，尽管接受了适当的结核病治疗，但淋巴结病和脾肿大仍逐渐加重。该患者经PET/CT和腋窝淋巴结活检后被诊断为HL。
