Brunsvold M, Tomasovic J, Ruemping D
ASDC J Dent Child. 1985 Nov-Dec;52(6):417-21.
Gingival enlargement was studied and measured in ten patients before, and for 18 months after discontinuation of phenytoin therapy. A clinically evident decrease in gingival hyperplasia occurred after discontinuing phenytoin in all subjects; all subjects, however, had mild hyperplasia after 18 months. These results may encourage increased use of alternative antiseizure drugs.
对10名患者在停用苯妥英钠治疗前及停药后18个月进行了牙龈增大情况的研究和测量。所有受试者停用苯妥英钠后，牙龈增生在临床上均有明显减轻；然而，所有受试者在18个月后仍有轻度增生。这些结果可能会促使更多地使用替代抗癫痫药物。
