Steinberg S C, Steinberg A D
J Periodontol. 1982 Jul;53(7):429-33. doi: 10.1902/jop.1982.53.7.429.
Nineteen severely retarded children were studied to evaluate distribution, severity and control of phenytoin-induced gingival overgrowth (PIGO). Observations included the Plaque Index, the Gingival Index and the PIGO Index. Eighteen of these patients had gingival overgrowth with 47% having the severest type of involvement and all having severe overgrowth in the posterior regions. Elimination of topical, oral contact of phenytoin did not appear to alter gingival overgrowth. Use of SnF2 as an antiplaque agent significantly decreased plaque and overgrowth scores. Use of an electric toothbrush quite significantly decreased gingival inflammation, plaque scores and gingival overgrowth.
对19名重度智障儿童进行了研究,以评估苯妥英钠所致牙龈增生(PIGO)的分布、严重程度及控制情况。观察指标包括菌斑指数、牙龈指数和PIGO指数。其中18名患者出现牙龈增生,47%的患者为最严重的受累类型,且所有患者后部区域均有严重增生。消除苯妥英钠的局部口腔接触似乎并未改变牙龈增生情况。使用含氟牙膏作为防菌斑剂可显著降低菌斑和增生评分。使用电动牙刷可非常显著地减轻牙龈炎症、降低菌斑评分并减少牙龈增生。