In vitro dissolution of human enamel after application of a mixture of stannous fluoride and amine fluoride 297: a pilot study.

Human enamel specimens were topically treated in vitro, using either a clear, aged aqueous mixture consisting of SnF2 and amine fluoride 297, or SnF2 alone, amine fluoride 297 alone, NaF, or water (as the negative control). The fluoride concentrations used were 250 ppm F1/n. The topically treated enamel specimens were then acid-etched for 5, 10, 15, and 15 seconds, respectively, in 2NHC1. The amount of phosphorous dissolved from the enamel and the depth of etch were both significantly less for the groups treated with SnF2/AmF297 and SnF2 alone, which indicated better protection against acid dissolution than the other three groups.