术前西咪替丁和雷尼替丁对胃液分泌的影响。
Effect of preoperative cimetidine and ranitidine on gastric secretion.
作者信息
Royer J E, Triplett R G
出版信息
J Oral Maxillofac Surg. 1985 Dec;43(12):956-7. doi: 10.1016/0278-2391(85)90010-2.
PMID:3864950
Abstract
To decrease gastric volume and acidity prior to anesthesia and surgery and decrease the risk of aspiration, a prospective double-blind trial comparing two H2 receptor blockers, cimetidine and ranitidine, was performed. Analysis of gastric contents revealed both drugs to be extremely effective in raising gastric pH to the 6-7 range. However, ranitidine was shown to be more effective in decreasing gastric volume.
摘要
为了在麻醉和手术前减少胃容量和酸度，并降低误吸风险，进行了一项前瞻性双盲试验，比较两种H2受体阻滞剂西咪替丁和雷尼替丁。对胃内容物的分析表明，两种药物在将胃pH值提高到6-7范围方面都极其有效。然而，雷尼替丁在减少胃容量方面更有效。
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