University of Sao Paulo, Department of Neurosurgery, Sao Paulo, Brazil.
Turk Neurosurg. 2024;34(3):388-392. doi: 10.5137/1019-5149.JTN.43614-23.4.
To investigate the possible relationship between intracranial aneurysms and brain neoplasms.
A comprehensive literature review involving a search of the databases PubMed and Embase to identify relevant articles was conducted in March 2021. The initial search retrieved 451 articles. After deduplication and screening of abstracts, 56 articles were selected. After reading of the full texts, 19 articles were included in the review.
There insufficient evidence to support that people with brain neoplasms have a higher incidence rate of IAs. However, the prevalence of IAs appears to be higher in patients with pituitary tumors than in the general population. The key factors affecting prognosis were tumor type in patients with unruptured aneurysms and progression of subarachnoid hemorrhage in individuals with ruptured aneurysms. Treatment should be individualized according to patient age, tumor pathology, location, and aneurysm rupture risk.
There is a lack of evidence to affirm that the existence of brain neoplasm plays a role in the formation and rupture of intracranial aneurysms. Additionally, there is insufficient evidence to confirm a greater prevalence of intracranial aneurysms in individuals with brain tumors. The association of these two disorders does not appear to worsen patient outcome. Prognosis depends on tumor pathology for malignant cases and on subarachnoid hemorrhage in patients with ruptured aneurysms.
探讨颅内动脉瘤与脑肿瘤之间的可能关系。
2021 年 3 月，我们进行了全面的文献回顾，检索了 PubMed 和 Embase 数据库，以确定相关文章。初始搜索共检索到 451 篇文章。经过去重和摘要筛选，选择了 56 篇文章。在阅读全文后，有 19 篇文章纳入综述。
目前尚无充分证据支持脑肿瘤患者颅内动脉瘤的发病率更高。然而，垂体瘤患者颅内动脉瘤的患病率似乎高于普通人群。影响预后的关键因素是未破裂动脉瘤患者的肿瘤类型和破裂动脉瘤患者的蛛网膜下腔出血进展。治疗应根据患者年龄、肿瘤病理、位置和动脉瘤破裂风险个体化进行。
目前尚无证据可以肯定脑肿瘤的存在在颅内动脉瘤的形成和破裂中起作用。此外，也没有足够的证据可以证实脑肿瘤患者颅内动脉瘤的患病率更高。这两种疾病的关联似乎不会使患者的预后恶化。对于恶性肿瘤，预后取决于肿瘤病理，对于破裂动脉瘤患者，取决于蛛网膜下腔出血。
