Atallah Oday, Alrefaie Khadeja, Badary Amr
Department of Neurosurgery, Evangelic Hospital Oldenburg, Carl Von Ossietzky University Oldenburg, 26111 Oldenburg, Germany.
Medical School Hannover, 30625 Hannover, Germany.
Cancers (Basel). 2025 Sep 4;17(17):2908. doi: 10.3390/cancers17172908.
The simultaneous occurrence of brain aneurysms and brain tumors creates a complicated clinical scenario requiring extensive surgical planning. The study seeks to illuminate the safety, effectiveness, and prospective advantages of combination surgical intervention.
We analyzed 10 patients concurrently diagnosed with both cerebral aneurysm and meningioma who received simultaneous microsurgical intervention. Clinical and demographic data, encompassing lesion characteristics, surgical specifics, complications, and outcomes, was extracted. The Karnofsky Performance Status Scale (KPS) was utilized to assess functional status preoperatively, after discharge, and during the final follow-up. Descriptive statistics and visualizations were produced via Python tools and libraries.
The predominant demographic was female (90%), with a median surgical age of 58 years. All patients presented with WHO Grade 1 meningiomas and predominantly incidental aneurysms, typically situated in the middle cerebral artery. At a median follow-up of 27 months, functional results demonstrated improvement, with 10% of patients reporting tumor recurrence or necessitating resurgery, while the total death rate was 20%.
The simultaneous occurrence of intracranial aneurysms and brain tumors is infrequent. This study demonstrates that simultaneous aneurysm clipping and tumor resection with the same method is both viable and secure. A comprehensive evaluation of the patient and an extensively devised surgical plan are essential for the effective management of these complex cases.
脑动脉瘤和脑肿瘤同时出现会产生复杂的临床情况，需要进行广泛的手术规划。本研究旨在阐明联合手术干预的安全性、有效性和潜在优势。
我们分析了10例同时诊断为脑动脉瘤和脑膜瘤并接受同期显微手术干预的患者。提取了临床和人口统计学数据，包括病变特征、手术细节、并发症和结果。采用卡诺夫斯基功能状态量表（KPS）评估术前、出院后及末次随访时的功能状态。通过Python工具和库进行描述性统计和可视化。
主要人群为女性（90%），手术年龄中位数为58岁。所有患者均为世界卫生组织1级脑膜瘤，且主要为偶然发现的动脉瘤，通常位于大脑中动脉。中位随访27个月时，功能结果显示有所改善，10%的患者报告肿瘤复发或需要再次手术，总死亡率为20%。
颅内动脉瘤和脑肿瘤同时出现的情况并不常见。本研究表明，采用相同方法同期进行动脉瘤夹闭和肿瘤切除是可行且安全的。对患者进行全面评估并制定广泛的手术计划对于有效管理这些复杂病例至关重要。
