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[Association of antigens of the histocompatibility system in A and B loci in systemic lupus erythematosus].

作者信息

Lesniak O M

出版信息

Ter Arkh. 1985;57(8):136-8.

PMID:3865447
Abstract

The typing of histocompatibility HLA-B and A antigens was made in 63 patients with systemic lupus erythematosus (SLE). It was shown that the carriership of some histocompatibility antigens and association of definite antigens, in particular, increases the relative risk of the development of SLE. This was especially applicable to the following gene combinations: HLA-B-8/B12, HLA-B-18/10, HIA-AII/AI/A3 and some others. Definite associations were revealed between carriership of some histocompatibility antigens and development of some manifestations of SLE.

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